The Maryanovich Lab
The Team
Dr. Maria Maryanovich, Ph.D.
Principal Investigator
Dr. Maria Maryanovich is an Assistant Professor in the Department of Cell Biology and a member of two institutes at Albert Einstein College of Medicine: 1) The Gottesman Institute for Stem Cell Biology and Regenerative Medicine, and 2) The Institute of Cancer Dormancy and Tumor Microenvironment. After graduating from the Ort Braude College of Engineering with a degree in Biotechnology Engineering she moved to the Weizmann Institute of Science, completing her Ph.D. in the lab of Prof. Atan Gross where she focused on how mitochondria metabolism regulates hematopoietic stem cell quiescence and function. She then joined the lab of Dr. Paul S. Frenette at Einstein for her postdoctoral studies, where she discovered the critical role of sympathetic nerves
and adrenergic signaling within the bone marrow in regulating the hematopoietic niche during aging.
Maria's goal for the lab is to uncover the cellular and molecular regulators of HSCs within the niche in both normal hematopoiesis and in the context of aging and myeloid leukemia. Dr. Maryanovich is also dedicated to training the next generation of scientists and providing a supportive lab environment in the long-standing tradition of her former mentor Dr. Paul Frenette.
Dr. Randall S. Carpenter, Ph.D.
Postdoctoral Research Fellow
Dr. Randall Carpenter is a Postdoctoral Research Fellow in the Maryanovich Lab. Randall graduated from Loyola University Chicago in 2009 with a B.S. in Biology, B.A. in Music, and minor in Neuroscience. After graduation he worked as a technician in the lab of Dr. Agnieszka Ardelt at the University of Chicago, and entered the Neuroscience Graduate Program at The Ohio State University in 2013. Randall's Ph.D. training, in the lab of Dr. Phillip Popovich, was on the neuro-immune consequences of spinal cord injury. He implemented "humanized" mouse models to study the human immune response to injury, and also discovered that spinal cord injury causes a chronic bone marrow failure syndrome marked by impaired hematopoietic stem cell function and mobilization.
Randall started his postdoc in the lab of Dr. Paul Frenette in 2019 and joined the Maryanovich lab in the summer of 2022. His research focuses on the circadian regulation of hematopoietic progenitors by the sympathetic nervous system.
Francesca Licausi, M.S.
Graduate Student
Francesca is a predoctoral candidate in the Maryanovich lab. Francesca graduated from Stockton University in 2018 with a B.S in Biology and minor in neuroscience. Following graduation, she received a Post-baccalaureate Intermural Research Training Award from the National Institutes of Health. In 2018, Francesca joined the laboratory of Dr. Robert Colbert as a research trainee, where she examined how a disease risk variant of spondolyoarthritis influenced mesenchymal stem cell fate and osteogenic differentiation. In 2019, she joined the laboratory of Dr. Zu-hang Sheng and examined how intercellular communication between oligodendrocytes and neurons influenced axonal metabolism. Francesca entered the Ph.D. program at Albert Einstein College of Medicine in 2020 and
completed her Masters in Cell Biology in the laboratory of Dr. Richard Kitsis studying mitochondrial mediated cell death. After completing her masters, Francesca joined the Maryanovich lab in August of 2022, where she is investigating intercellular communication and ROS signaling in the hematopoietic niche, with a focus on mesenchymal stem cells.
Mahamudun Bhuiyan, B.S.
Research Technician
Mahamudun Bhuiyan is our Research Technician in the Maryanovich lab. Mahamudun graduated from the City College of New York with a B.S. in Biology and a minor in Economics. In addition to his course work at the New York Academy of Sciences, Mahamudun completed two projects and presented these to prominent scientists, such as James Watson, and CEOs of Fortune 500 companies such as Coca-Cola. One project studied the effects of drinking alcohol on the neuronal firing rate of earthworms and how this can be correlated to its effects on humans. The second project explored methods of maximizing the use of freshwater for both laymen and large companies at the academy’s Challenge 2030 event. Mahamudun joined the Maryanovich lab in the August of 2022 with hopes to garner
research experience to enter a prospective PhD program. As the lab research technician, Mahamudun is responsible for maintaining basic lab supplies & reagents, performing mouse husbandry, and is training to become proficient in confocal microscopy.
Farzana Begum, B.S.
Graduate Student
Farzana Begum, is a Ph.D. Graduate Student here at Albert Einstein College of Medicine. Farzana graduated from Manhattan College in 2020 with a B.S in Chemical Engineering and a minor in Mathematics. Following graduation, she began working at Eurofins Lancaster Laboratories as a chemist where she worked on developing lipid nanoparticle formulations for various mRNA vaccines and therapeutics. In 2021, Farzana joined the Viral Vaccines department of Pfizer as an associate scientist to work on propagating, characterizing, and quantifying various viruses for vaccine development. After her time as an associate scientist, Farzana entered the Ph.D. program at Albert Einstein College of Medicine in 2022.
Farzana has now joined the Maryanovich lab and is working on investigating the mechanisms behind the effect of ROS on the immune response to acute myeloid leukemia.
Previous Members
Roshan Mathews M.S. - Rotation Student